Cost - G10 can be expensive compared to metals like aluminum or steel, making it less suitable for small projects. 

Rigidity - G10 can be difficult to work with due to its rigidity and high fiber content. 

UV resistance - G10 can break down over time with prolonged exposure to UV rays, which can affect its appearance and mechanical properties. A UV resistant coating can help mitigate this. 

Dust - When cut or sanded, G10 can create dust that can irritate the skin and eyes. Wearing protective gear is recommended. 

FR4 dimensional stability - FR4's dimensional stability can degrade at high temperatures, voltages, and powers.